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MXD4 Protein (His tag)

MXD4 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2725129
  • Target See all MXD4 Proteins
    MXD4 (MAX Dimerization Protein 4 (MXD4))
    Protein Type
    Recombinant
    Origin
    • 2
    • 1
    Human
    Source
    • 2
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This MXD4 protein is labelled with His tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human MAD4 (full length, N-term HIS tag) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product MXD4 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the N-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    MXD4 (MAX Dimerization Protein 4 (MXD4))
    Alternative Name
    Mad4 (MXD4 Products)
    Synonyms
    MAD4 Protein, MST149 Protein, MSTP149 Protein, bHLHc12 Protein, xmad4 Protein, mst149 Protein, bhlhc12 Protein, mstp149 Protein, MGC84841 Protein, MXD4 Protein, 2810410A03Rik Protein, Mad4 Protein, MAX dimerization protein 4 Protein, Max dimerization protein 4 Protein, MAX dimerization protein 4 S homeolog Protein, microRNA 4800 Protein, MXD4 Protein, Mxd4 Protein, mxd4.S Protein, MIR4800 Protein, mxd4 Protein
    Background
    This gene is a member of the MAD gene family. The MAD genes encode basic helix-loop-helix-leucine zipper proteins that heterodimerize with MAX protein, forming a transcriptional repression complex. The MAD proteins compete for MAX binding with MYC, which heterodimerizes with MAX forming a transcriptional activation complex. Studies in rodents suggest that the MAD genes are tumor suppressors and contribute to the regulation of cell growth in differentiating tissues.
    Molecular Weight
    23.3 kDa
    NCBI Accession
    NP_006445
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