MAPK10 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2725410

Product Details

Target: MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 2

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This MAPK10 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human MAPK10 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: MAPK10 (Mitogen-Activated Protein Kinase 10 (MAPK10))

Alternative Name: Mapk10 (MAPK10 Products)

Synonyms: MAPK10 Protein, zgc:123234 Protein, DKFZp459H0638 Protein, Jnk3 Protein, SAPKC Protein, SAPb Protein, Serk2 Protein, JNK3 Protein, JNK3A Protein, PRKM10 Protein, SAPK1b Protein, p493F12 Protein, p54bSAPK Protein, C230008H04Rik Protein, JNK3B1 Protein, JNK3B2 Protein, SAPK(beta) Protein, ATMPK10 Protein, MAP kinase 10 Protein, mitogen-activated protein kinase 8 S homeolog Protein, mitogen-activated protein kinase 10 Protein, mitogen activated protein kinase 10 Protein, MAP kinase 10 Protein, mapk8.S Protein, MAPK10 Protein, mapk10 Protein, Mapk10 Protein, MPK10 Protein

Background: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as integration points for multiple biochemical signals and are involved in a wide variety of cellular processes, such as proliferation, differentiation, transcription regulation and development. This kinase is specifically expressed in a subset of neurons in the nervous system and is activated by threonine and tyrosine phosphorylation. Targeted deletion of this gene in mice suggests that it may have a role in stress-induced neuronal apoptosis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon.

Molecular Weight: 52.4 kDa

NCBI Accession: NP_620448

Pathways: MAPK Signaling, WNT Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades