MATK Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all MATK Proteins
- MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This MATK protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human MATK (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product MATK Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- MATK (Megakaryocyte-Associated tyrosine Kinase (MATK))
- Alternative Name
- Matk (MATK Products)
- Synonyms
- si:ch211-63j24.2 Protein, CHK Protein, CTK Protein, HHYLTK Protein, HYL Protein, HYLTK Protein, Lsk Protein, Ntk Protein, Batk Protein, megakaryocyte-associated tyrosine kinase Protein, zinc finger RNA binding protein 2 Protein, matk Protein, MATK Protein, Matk Protein, ZFR2 Protein
- Background
- The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene.
- Molecular Weight
- 56.3 kDa
- NCBI Accession
- NP_647612
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