MATR3 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2725552

Product Details

Target: MATR3 (Matrin 3 (MATR3))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 2

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This MATR3 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human Matrin-3 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

References

Johnson, Pioro, Boehringer, Chia, Feit, Renton, Pliner, Abramzon, Marangi, Winborn, Gibbs, Nalls, Morgan, Shoai, Hardy, Pittman, Orrell, Malaspina, Sidle, Fratta, Harms, Baloh, Pestronk, Weihl et al.: "Mutations in the Matrin 3 gene cause familial amyotrophic lateral sclerosis. ..." in: Nature neuroscience, Vol. 17, Issue 5, pp. 664-6, (2014) (PubMed).

Target Details

Target: MATR3 (Matrin 3 (MATR3))

Alternative Name: Matrin-3 (MATR3 Products)

Synonyms: MPD2 Protein, VCPDM Protein, 1110061A14Rik Protein, 2810017I02Rik Protein, AI841759 Protein, AW555618 Protein, D030046F20Rik Protein, mKIAA0723 Protein, P130/MAT3 Protein, matrin-3 Protein, matr3 Protein, MGC79524 Protein, MATR3 Protein, DKFZp459A057 Protein, DKFZp459A162 Protein, DKFZp459F0515 Protein, DKFZp469A1933 Protein, LOC100232255 Protein, KIAA0723 Protein, matrin 3 Protein, matrin 3 S homeolog Protein, MATR3 Protein, Matr3 Protein, matr3.S Protein, matr3 Protein

Background: This gene encodes a nuclear matrix protein, which is proposed to stabilize certain messenger RNA species. Mutations of this gene are associated with distal myopathy 2, which often includes vocal cord and pharyngeal weakness. Alternatively spliced transcript variants, including read-through transcripts composed of the upstream small nucleolar RNA host gene 4 (non-protein coding) and matrin 3 gene sequence, have been identified. Pseudogenes of this gene are located on chromosomes 1 and X.

Molecular Weight: 94.4 kDa

NCBI Accession: NP_061322