ZAK Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Target See all ZAK Proteins
- ZAK (Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This ZAK protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human MLTK (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product ZAK Protein
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Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK) (AA 1-455) protein (GST tag)
ZAK Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP, KAA
Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK) (AA 1-455) (Active) protein (GST tag)ZAK Origin: Human Host: Insect cells (Sf21) Recombinant SDS, Func Active
Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK) (AA 1-120) protein (GST tag)ZAK Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP
Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK) (AA 1-800) protein (Strep Tag)Crystallography grade ZAK Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK) (AA 1-802) protein (Strep Tag)Crystallography grade ZAK Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)ZAK Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- ZAK (Mitogen-Activated Protein Kinase Kinase Kinase MLT (ZAK))
- Alternative Name
- Mltk (ZAK Products)
- Synonyms
- MLTK Protein, RGD1561394 Protein, AZK Protein, MLK7 Protein, MLT Protein, MRK Protein, mlklak Protein, pk Protein, AV006891 Protein, B230120H23Rik Protein, MLTKalpha Protein, MLTKbeta Protein, mitogen-activated protein kinase kinase kinase 20 Protein, Map3k20 Protein, MAP3K20 Protein
- Background
- This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
- Molecular Weight
- 51.4 kDa
- NCBI Accession
- NP_598407
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