MMP14 Protein (Myc-DYKDDDDK Tag)
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- Target See all MMP14 Proteins
- MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This MMP14 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human MMP-14 / MT1-MMP protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product MMP14 Protein
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Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14) (AA 1-501) protein (His tag)
MMP14 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14) (AA 1-582) protein (GST tag)MMP14 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14) (AA 112-541) protein (His tag)Crystallography grade MMP14 Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14) (AA 112-541) protein (His tag)Crystallography grade MMP14 Origin: Mouse Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14) (AA 112-582) protein (rho-1D4 tag)Crystallography grade MMP14 Origin: Human Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14) (AA 112-582) protein (rho-1D4 tag)Crystallography grade MMP14 Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- MMP14 (Matrix Metallopeptidase 14 (Membrane-inserted) (MMP14))
- Alternative Name
- Mmp-14,mt1-Mmp (MMP14 Products)
- Synonyms
- MMP1 Protein, MMP-14 Protein, MMP-X1 Protein, MT-MMP Protein, MT-MMP 1 Protein, MT1-MMP Protein, MT1MMP Protein, MTMMP1 Protein, mmp-x1 Protein, mt1-mmp Protein, mtmmp1 Protein, AI325305 Protein, MT-MMP-1 Protein, sabe Protein, Mt1-mmp Protein, MT-MMPbeta Protein, cb386 Protein, sb:cb386 Protein, wu:fb72b09 Protein, mmp14 Protein, matrix metallopeptidase 14 Protein, matrix metallopeptidase 14 (membrane-inserted) Protein, matrix metallopeptidase 14b (membrane-inserted) Protein, matrix metallopeptidase 14a (membrane-inserted) Protein, matrix metallopeptidase 14 L homeolog Protein, MMP14 Protein, mmp14 Protein, Mmp14 Protein, mmp14b Protein, mmp14a Protein, mmp14.L Protein
- Background
- Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein, and this activity may be involved in tumor invasion.
- Molecular Weight
- 53.8 kDa
- NCBI Accession
- NP_004986
- Pathways
- Autophagy
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