NAD-ME Protein (Myc-DYKDDDDK Tag)
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- Target See all NAD-ME Proteins
- NAD-ME (NAD Dependent Malate Dehydrogenase (NAD-ME))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This NAD-ME protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human NAD-ME protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product NAD-ME Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- NAD-ME (NAD Dependent Malate Dehydrogenase (NAD-ME))
- Alternative Name
- Nad-Me (NAD-ME Products)
- Synonyms
- ODS1 Protein, AW120568 Protein, D030040L20Rik Protein, NAD-ME Protein, zgc:100941 Protein, malic enzyme 2 Protein, malic enzyme 2, NAD(+)-dependent, mitochondrial Protein, malic enzyme 2, NAD(+)-dependent, mitochondrial S homeolog Protein, ME2 Protein, Me2 Protein, me2.S Protein, me2 Protein
- Background
- This gene encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene.
- Molecular Weight
- 63.4 kDa
- NCBI Accession
- NP_002387
- Pathways
- Production of Molecular Mediator of Immune Response
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