NBL1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2726864

Product Details

Target: NBL1 (Neuroblastoma 1, DAN Family BMP Antagonist (NBL1))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 2

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This NBL1 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human NBL1 (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: NBL1 (Neuroblastoma 1, DAN Family BMP Antagonist (NBL1))

Alternative Name: Nbl1 (NBL1 Products)

Synonyms: D1S1733E Protein, DAN Protein, DAND1 Protein, NB Protein, NO3 Protein, D4H1S1733E Protein, Dana Protein, dand1 Protein, nbl1-a Protein, no3 Protein, 4.1N Protein, Epb41l1 Protein, NBL1 Protein, mKIAA0338 Protein, C1orf151-NBL1 Protein, dan Protein, zgc:77251 Protein, neuroblastoma 1, DAN family BMP antagonist Protein, neuroblastoma, suppression of tumorigenicity 1 Protein, neuroblastoma 1, DAN family BMP antagonist L homeolog Protein, neuroblastoma suppressor of tumorigenicity 1 Protein, erythrocyte membrane protein band 4.1 like 1 Protein, MINOS1-NBL1 readthrough Protein, NBL1 Protein, Nbl1 Protein, nbl1.L Protein, LOC535280 Protein, Epb41l1 Protein, MINOS1-NBL1 Protein, nbl1 Protein

Background: This gene product is the founding member of the evolutionarily conserved CAN (Cerberus and DAN) family of proteins, which contain a domain resembling the CTCK (C-terminal cystine knot-like) motif found in a number of signaling molecules. These proteins are secreted, and act as BMP (bone morphogenetic protein) antagonists by binding to BMPs and preventing them from interacting with their receptors. They may thus play an important role during growth and development. Alternatively spliced transcript variants have been identified for this gene. Read-through transcripts between this locus and the upstream mitochondrial inner membrane organizing system 1 gene (GeneID 440574) have been observed.

Molecular Weight: 17.6 kDa

NCBI Accession: NP_005371