NME1 Protein (Transcript Variant 2) (His tag)

Catalog No. ABIN2726967

Product Details

Target: NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 2

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This NME1 protein is labelled with His tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human NDP kinase A (transcript variant 2) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Purity: > 95 % as determined by SDS-PAGE and Coomassie blue staining

Endotoxin Level: < 0.1 EU per μg protein as determined by LAL test

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 20 mM Tris-HCl, 1 mM DTT, 10 % Glycerol, pH 7.5. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: NME1 (Non-Metastatic Cells 1, Protein (NM23A) Expressed in (NME1))

Alternative Name: Ndp Kinase A (NME1 Products)

Synonyms: AWD Protein, GAAD Protein, NB Protein, NBS Protein, NDKA Protein, NDPK-A Protein, NDPKA Protein, NM23 Protein, NM23-H1 Protein, AL024257 Protein, NM23-M1 Protein, NM23A Protein, NDPK-Z1 Protein, NM23-B Protein, NM23-Z1 Protein, ndpkz1 Protein, nm23b Protein, nme1 Protein, nme2 Protein, nme2b1 Protein, NME1 Protein, NME1-NME2 Protein, NM23-C1 Protein, ndpk-b Protein, ndpkb Protein, nm23-h2 Protein, nm23ndk Protein, puf Protein, NBR-A Protein, NBR-B Protein, NME1-1 Protein, nm23ndk-a Protein, NDK I Protein, NDPK I Protein, T30A10.80 Protein, T30A10_80 Protein, NDP kinase I Protein, NME/NM23 nucleoside diphosphate kinase 1 Protein, NME/NM23 nucleoside diphosphate kinase 2b, tandem duplicate 1 Protein, non-metastatic cells 1, protein (NM23A) expressed in Protein, NME/NM23 nucleoside diphosphate kinase 2 S homeolog Protein, NME/NM23 nucleoside diphosphate kinase 2 L homeolog Protein, nucleoside diphosphate kinase Protein, nucleoside diphosphate kinase 1 Protein, NME1 Protein, Nme1 Protein, nme2b.1 Protein, nme2.S Protein, nme2.L Protein, LOC547870 Protein, NDPK1 Protein, LOC107790563 Protein

Background: This gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of &aposA&apos (encoded by this gene) and &aposB&apos (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co-transcription of this gene and the neighboring downstream gene (NME2) generates naturally-occurring transcripts (NME1-NME2), which encodes a fusion protein comprised of sequence sharing identity with each individual gene product.

Molecular Weight: 19.3 kDa

NCBI Accession: NP_000260

Pathways: Apoptosis, Nucleotide Phosphorylation, Carbohydrate Homeostasis, Ribonucleoside Biosynthetic Process