NK2 Homeobox 5 Protein (NKX2-5) (Myc-DYKDDDDK Tag)
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- Target See all NK2 Homeobox 5 (NKX2-5) Proteins
- NK2 Homeobox 5 (NKX2-5)
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This NK2 Homeobox 5 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human NKX2-5 protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product NKX2-5 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- NK2 Homeobox 5 (NKX2-5)
- Alternative Name
- Nkx2-5 (NKX2-5 Products)
- Synonyms
- CHNG5 Protein, CSX Protein, CSX1 Protein, HLHS2 Protein, NKX2.5 Protein, NKX2E Protein, NKX4-1 Protein, VSD3 Protein, Csx Protein, Nkx-2.5 Protein, Nkx2.5 Protein, tinman Protein, nk2.5 Protein, nkx2-5 Protein, zgc:111912 Protein, AR2 Protein, XNkx2-5 Protein, csx Protein, nkx-2.5 Protein, nkx2-5b Protein, nkx2.5 Protein, NKX2-5 Protein, Nkx2-5 Protein, csx1 Protein, nkx2e Protein, XNkx-2.5 Protein, CNKX-2.5 Protein, NKX-2.5 Protein, NK2 homeobox 5 Protein, NK2 homeobox 5 S homeolog Protein, NKX2-5 Protein, Nkx2-5 Protein, nkx2.5 Protein, nkx2-5.S Protein, nkx2-5 Protein
- Background
- This gene encodes a homeobox-containing transcription factor. This transcription factor functions in heart formation and development. Mutations in this gene cause atrial septal defect with atrioventricular conduction defect, and also tetralogy of Fallot, which are both heart malformation diseases. Mutations in this gene can also cause congenital hypothyroidism non-goitrous type 5, a non-autoimmune condition. Alternative splicing results in multiple transcript variants.
- Molecular Weight
- 34.7 kDa
- NCBI Accession
- NP_004378
- Pathways
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
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