NUMB Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all NUMB Proteins
- NUMB (Numb Homolog (NUMB))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This NUMB protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human NUMB (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product NUMB Protein
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Numb Homolog (NUMB) (AA 1-135) protein (GST tag)
NUMB Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Numb Homolog (NUMB) (AA 1-651) protein (Strep Tag)Crystallography grade NUMB Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Numb Homolog (NUMB) (AA 1-653) protein (Strep Tag)Crystallography grade NUMB Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
Numb Homolog (NUMB) protein (DYKDDDDK Tag)NUMB Origin: Human Host: Insect cells (Sf9) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Numb Homolog (NUMB) proteinNUMB Origin: Mouse Host: Escherichia coli (E. coli) Recombinant > 95 % WB, SDS, ELISA, IP
Numb Homolog (NUMB) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)NUMB Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- NUMB (Numb Homolog (NUMB))
- Alternative Name
- Numb (NUMB Products)
- Synonyms
- C14orf41 Protein, S171 Protein, c14_5527 Protein, Nb Protein, NUMB, endocytic adaptor protein Protein, numb homolog (Drosophila) Protein, NUMB Protein, Numb Protein, numb Protein
- Background
- Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage. [UniProtKB/Swiss-Prot Function]
- Molecular Weight
- 70.6 kDa
- NCBI Accession
- NP_001005743
- Pathways
- Cell-Cell Junction Organization
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