OAS1 Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Target See all OAS1 Proteins
- OAS1 (2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This OAS1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human OAS1 / OIAS (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product OAS1 Protein
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2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 1-400) protein (GST tag)
OAS1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 1-364) protein (His tag)OAS1 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 1-100) protein (GST tag)OAS1 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1) (AA 1-400) protein (Strep Tag)Crystallography grade OAS1 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- OAS1 (2',5'-Oligoadenylate Synthetase 1, 40/46kDa (OAS1))
- Alternative Name
- Oas1,oias (OAS1 Products)
- Synonyms
- OAS1 Protein, IFI-4 Protein, OIAS Protein, OIASI Protein, L3 Protein, Pp2a2 Protein, 2',5'-oligoadenylate synthetase 1 Protein, 2'-5'-oligoadenylate synthetase 1 Protein, 2'-5' oligoadenylate synthetase 1A Protein, protein phosphatase 2 catalytic subunit beta Protein, OAS1 Protein, Oas1a Protein, Ppp2cb Protein, Oas1 Protein
- Background
- This gene is induced by interferons and encodes a protein that synthesizes 2&apos,5&apos-oligoadenylates (2-5As). This protein activates latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. Alternative splicing results in multiple transcript variants with different enzymatic activities. Polymorphisms in this gene have been associated with susceptibility to viral infection and diabetes mellitus, type 1. A disease-associated allele in a splice acceptor site influences the production of the p46 splice isoform. This gene is located in a cluster of related genes on chromosome 12.
- Molecular Weight
- 41.6 kDa
- NCBI Accession
- NP_002525
- Pathways
- Hepatitis C
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