OLR1 Protein (Transcript Variant 2)
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- Target See all OLR1 Proteins
- OLR1 (Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 2
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Origin
- Human
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Source
- HEK-293 Cells
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human OLR1 / LOX1 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 95 % as determined by SDS-PAGE and Coomassie blue staining
- Endotoxin Level
- < 0.1 EU per μg protein as determined by LAL test
- Top Product
- Discover our top product OLR1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Restrictions
- For Research Use only
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- Buffer
- Lyophilized from a 0.2 μM filtered solution of 20 mM Phosphate buffer, 150 mM NaCl, pH 7.2. Stable for at least 6 months from date of receipt under proper storage and handling conditions.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- OLR1 (Oxidized Low Density Lipoprotein (Lectin-Like) Receptor 1 (OLR1))
- Alternative Name
- Olr1,lox1 (OLR1 Products)
- Synonyms
- OLR1 Protein, LOX1 Protein, Olr1 Protein, CLEC8A Protein, LOXIN Protein, SCARE1 Protein, SLOX1 Protein, LOX-1 Protein, SR-EI Protein, Scare1 Protein, Oldlr1 Protein, Oldr1 Protein, PLOX-1 Protein, oxidized low density lipoprotein receptor 1 Protein, oxidized low density lipoprotein (lectin-like) receptor 1 Protein, OLR1 Protein, Olr1 Protein
- Background
- This gene encodes a low density lipoprotein receptor that belongs to the C-type lectin superfamily. This gene is regulated through the cyclic AMP signaling pathway. The encoded protein binds, internalizes and degrades oxidized low-density lipoprotein. This protein may be involved in the regulation of Fas-induced apoptosis. This protein may play a role as a scavenger receptor. Mutations of this gene have been associated with atherosclerosis, risk of myocardial infarction, and may modify the risk of Alzheimer&aposs disease. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Feb 2010]
- Molecular Weight
- 25.4 kDa
- NCBI Accession
- NP_001166103
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