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ORC2 Protein (Myc-DYKDDDDK Tag)

ORC2 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2727927
  • Target See all ORC2 Proteins
    ORC2 (Origin Recognition Complex Subunit 2 (ORC2))
    Protein Type
    Recombinant
    Origin
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 3
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This ORC2 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human ORC2 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product ORC2 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    ORC2 (Origin Recognition Complex Subunit 2 (ORC2))
    Alternative Name
    Orc2 (ORC2 Products)
    Synonyms
    CG3041 Protein, DmORC 2 Protein, DmORC2 Protein, DmOrc2 Protein, DmOrc2p Protein, Dmel\\CG3041 Protein, ORC Protein, ORC2 Protein, Orc-2 Protein, Orc2p Protein, fs(3)293 Protein, fs(3)293-19 Protein, k43 Protein, l(3)88Ab Protein, l(3)A5 Protein, l(3)K43 Protein, l(3)SG44 Protein, l(3)dsl5 Protein, l(3)k43 Protein, orc2 Protein, rDmORC Protein, ATORC2 Protein, F13M22.6 Protein, F13M22_6 Protein, ORIGIN RECOGNITION COMPLEX SECOND LARGEST SUBUNIT 2 Protein, origin recognition complex second largest subunit 2 Protein, ORC2L Protein, AU041563 Protein, Orc2l Protein, orc2-a Protein, orc2l Protein, xorc2 Protein, Origin recognition complex subunit 2 Protein, origin recognition complex second largest subunit 2 Protein, origin recognition complex subunit 2 Protein, origin recognition complex, subunit 2 Protein, origin recognition complex subunit 2 S homeolog Protein, Orc2 Protein, ORC2 Protein, orc2.S Protein, orc-2 Protein
    Background
    The origin recognition complex (ORC) is a highly conserved six subunits protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. This protein forms a core complex with ORC3, -4, and -5. It also interacts with CDC45 and MCM10, which are proteins known to be important for the initiation of DNA replication. This protein has been demonstrated to specifically associate with the origin of replication of Epstein-Barr virus in human cells, and is thought to be required for DNA replication from viral origin of replication. Alternatively spliced transcript variants have been found, one of which is a nonsense-mediated mRNA decay candidate.
    Molecular Weight
    65.8 kDa
    NCBI Accession
    NP_006181
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