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OTUB1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Recombinant OTUB1 protein expressed in HEK-293 Cells.
Catalog No. ABIN2728049
$956.40
Plus shipping costs $50.00, if applicable $20.00 dry ice
20 μg
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Quick Overview for OTUB1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag) (ABIN2728049)

Target

See all OTUB1 Proteins
OTUB1 (OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1))

Protein Type

Recombinant

Origin

  • 7
  • 3
  • 2
Human

Source

  • 9
  • 1
  • 1
  • 1
HEK-293 Cells

Application

Antibody Production (AbP), Standard (STD)

Purity

> 80 % as determined by SDS-PAGE and Coomassie blue staining
  • Protein Characteristics

    Transcript Variant 1

    Purification tag / Conjugate

    This OTUB1 protein is labelled with Myc-DYKDDDDK Tag.

    Characteristics

    • Recombinant human Otubain-1 (OTUB1) (transcript variant 1) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
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  • Application Notes

    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays

    Comment

    The tag is located at the C-terminal.

    Restrictions

    For Research Use only
  • Concentration

    50 μg/mL

    Buffer

    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

    Storage

    -80 °C

    Storage Comment

    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target

    OTUB1 (OTU Domain, Ubiquitin Aldehyde Binding 1 (OTUB1))

    Alternative Name

    Otubain-1 (Otub1)

    Background

    The product of this gene is a member of the OTU (ovarian tumor) superfamily of predicted cysteine proteases. The encoded protein is a highly specific ubiquitin iso-peptidase, and cleaves ubiquitin from branched poly-ubiquitin chains but not from ubiquitinated substrates. It interacts with another ubiquitin protease and an E3 ubiquitin ligase that inhibits cytokine gene transcription in the immune system. It is proposed to function in specific ubiquitin-dependent pathways, possibly by providing an editing function for polyubiquitin chain growth. Alternative splicing results in multiple transcript variants.

    Molecular Weight

    31.1 kDa

    NCBI Accession

    NP_060140
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