OTUD5 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2728059

Product Details

Target: OTUD5 (OTU Domain Containing 5 (OTUD5))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 1

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This OTUD5 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human OTUD5 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: OTUD5 (OTU Domain Containing 5 (OTUD5))

Alternative Name: Otud5 (OTUD5 Products)

Synonyms: DUBA Protein, AA407879 Protein, AI553596 Protein, BB114028 Protein, DXImx46e Protein, Sfc7 Protein, otud5 Protein, si:bz30i22.1 Protein, si:rp71-30i22.1 Protein, zgc:154072 Protein, wu:fi28a06 Protein, zgc:100839 Protein, OTU deubiquitinase 5 Protein, OTU domain containing 5 Protein, OTU deubiquitinase 5a Protein, OTU deubiquitinase 5 S homeolog Protein, OTU deubiquitinase 5 L homeolog Protein, OTU deubiquitinase 5b Protein, OTUD5 Protein, Otud5 Protein, otud5a Protein, otud5.S Protein, otud5.L Protein, otud5b Protein

Background: This gene encodes a member of the OTU (ovarian tumor) domain-containing cysteine protease superfamily. The OTU domain confers deubiquitinase activity and the encoded protein has been shown to suppress the type I interferon-dependent innate immune response by cleaving the polyubiquitin chain from an essential type I interferon adaptor protein. Cleavage results in disassociation of the adaptor protein from a downstream signaling complex and disruption of the type I interferon signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been described.

Molecular Weight: 60.4 kDa

NCBI Accession: NP_060072