PTH Protein
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- Target See all PTH Proteins
- PTH (Parathyroid Hormone (PTH))
- Protein Type
- Recombinant
- Biological Activity
- Active
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Application
- Functional Studies (Func), Standard (STD), Antibody Production (AbP), Protein Interaction (PI)
- Specificity
- Optimal preservation of protein structure, post-translational modifications and functions.
- Characteristics
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- Recombinant human Parathyroid hormone / PTH protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Tested for bioactivity.
- Purity
- > 95 % as determined by SDS-PAGE and Coomassie blue staining
- Endotoxin Level
- < 0.1 EU per μg protein as determined by LAL test
- Biological Activity Comment
- Specific Activity of 1.0 x 104 IU/mg as calculated by the UMR106 cell/cAMP method.
- Top Product
- Discover our top product PTH Protein
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Parathyroid Hormone (PTH) (Active) protein
PTH Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS-PAGE Func Active
Parathyroid Hormone (PTH) (AA 32-115) protein (Fc Tag)PTH Origin: Human Host: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Parathyroid Hormone (PTH) (AA 32-115) (Active) protein (MBP tag,His tag)PTH Origin: Rat Host: Escherichia coli (E. coli) > 90 % AcA, CC Active
Parathyroid Hormone (PTH) (AA 32-115) protein (His-IF2DI Tag)PTH Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Parathyroid Hormone (PTH) (AA 32-115) protein (His tag)PTH Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE WB, ELISA
Parathyroid Hormone (PTH) (AA 1-115) protein (GST tag)PTH Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Parathyroid Hormone (PTH) (AA 32-115) protein (GST tag)PTH Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays - Restrictions
- For Research Use only
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- Buffer
- Lyophilized from a 0.2 μM filtered solution of 10 mM HAc-NaAc, 150 mM NaCl, 5 % Mannitol, pH 4.0. Stable for at least 6 months from date of receipt under proper storage and handling conditions.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- PTH (Parathyroid Hormone (PTH))
- Alternative Name
- Parathyroid Hormone,pth (PTH Products)
- Synonyms
- PTH1 Protein, Pthp Protein, PTH-(1-84) Protein, Pth1 Protein, Pthr1 Protein, PTH Protein, parathyroid hormone Protein, parathyroid hormone S homeolog Protein, PTH Protein, Pth Protein, pth.S Protein
- Target Type
- Hormone
- Background
- This gene encodes a member of the parathyroid family of proteins. The encoded preproprotein is proteolytically processed to generate a protein that binds to the parathyroid hormone/parathyroid hormone-related peptide receptor and regulates blood calcium and phosphate levels. Excess production of the encoded protein, known as hyperparathyroidism, can result in hypercalcemia and kidney stones. On the other hand, defective processing of the encoded protein may lead to hypoparathyroidism, which can result in hypocalcemia and numbness. Alternative splicing results in multiple transcript variants.
- Molecular Weight
- 9.4 kDa
- NCBI Accession
- NP_000306
- Pathways
- cAMP Metabolic Process, Regulation of Carbohydrate Metabolic Process
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