PAX8 Protein (Myc-DYKDDDDK Tag)
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- Target See all PAX8 Proteins
- PAX8 (Paired Box 8 (PAX8))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PAX8 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human PAX8 (transcript variant PAX8A) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PAX8 Protein
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Paired Box 8 (PAX8) (AA 141-250) protein (GST tag)
PAX8 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Paired Box 8 (PAX8) (AA 243-450) protein (His tag)PAX8 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % by SDS-PAGE gel analyses WB, ELISA
Paired Box 8 (PAX8) (AA 1-450) protein (GST tag)PAX8 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Paired Box 8 (PAX8) (AA 300-377) protein (GST tag)PAX8 Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Paired Box 8 (PAX8) (AA 1-450) protein (Strep Tag)Crystallography grade PAX8 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
Paired Box 8 (PAX8) (AA 1-457) protein (Strep Tag)Crystallography grade PAX8 Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, ELISA, SDS
Paired Box 8 (PAX8) (AA 1-287) protein (His tag)PAX8 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS - PAGE SDS
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- PAX8 (Paired Box 8 (PAX8))
- Alternative Name
- Pax8 (PAX8 Products)
- Synonyms
- PAX8 Protein, XPax-8 Protein, XPax8 Protein, pax-8 Protein, PAX-8 Protein, Pax-8 Protein, paired box 8 Protein, paired box 8 L homeolog Protein, PAX8 Protein, pax8 Protein, Pax8 Protein, pax8.L Protein
- Background
- This gene encodes a member of the paired box (PAX) family of transcription factors. Members of this gene family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in this gene have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described.
- Molecular Weight
- 48 kDa
- NCBI Accession
- NP_003457
- Pathways
- Thyroid Hormone Synthesis, Regulation of Hormone Metabolic Process, Stem Cell Maintenance, Tube Formation
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