PDE1A Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all PDE1A Proteins
- PDE1A (Phosphodiesterase 1A (PDE1A))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PDE1A protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human PDE1A (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PDE1A Protein
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Phosphodiesterase 1A (PDE1A) (AA 1-545) protein (GST tag)
PDE1A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Phosphodiesterase 1A (PDE1A) (AA 446-545) protein (GST tag)PDE1A Origin: Human Host: Wheat germ Recombinant WB, ELISA, AP, AA
Phosphodiesterase 1A (PDE1A) (AA 2-535) protein (His tag)Crystallography grade PDE1A Origin: Human Host: Escherichia coli (E. coli) Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
Phosphodiesterase 1A (PDE1A) (AA 1-565) protein (His tag)Crystallography grade PDE1A Origin: Mouse Host: Insect Cells Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. WB, SDS, ELISA, Crys
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- PDE1A (Phosphodiesterase 1A (PDE1A))
- Alternative Name
- Pde1a (PDE1A Products)
- Synonyms
- PDE1A Protein, CAM-PDE-1A Protein, HCAM-1 Protein, HCAM1 Protein, HSPDE1A Protein, AI987702 Protein, AW125737 Protein, 3'-RACEclone8phosphodiesterase1A Protein, 3-RACEclone8phosphodiesterase1A Protein, PDE1 Protein, phosphodiesterase 1A Protein, phosphodiesterase 1A, calmodulin-dependent Protein, PDE1A Protein, pde1a Protein, Pde1a Protein
- Background
- Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1 MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 [PubMed 11342109] Fidock et al., 2002 [PubMed 11747989]).[supplied by OMIM, Oct 2009].
- Molecular Weight
- 62.1 kDa
- NCBI Accession
- NP_005010
- Pathways
- Neurotrophin Signaling Pathway, cAMP Metabolic Process, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
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