PDE1C Protein (His tag)
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- Target See all PDE1C Proteins
- PDE1C (phosphodiesterase 1C, Calmodulin-Dependent 70kDa (PDE1C))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This PDE1C protein is labelled with His tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human PDE1C (N-term HIS tag, transcript variant 4) protein expressed in E. coli.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PDE1C Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the N-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 50 mM Tris,8M Urea, pH 8.0.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- PDE1C (phosphodiesterase 1C, Calmodulin-Dependent 70kDa (PDE1C))
- Alternative Name
- Pde1c (PDE1C Products)
- Synonyms
- CG14940 Protein, CG14942 Protein, CG14943 Protein, CG14944 Protein, CG31757 Protein, CG31758 Protein, CG42325 Protein, CG44007 Protein, Dmel\\CG44007 Protein, Dmel_CG14940 Protein, Dmel_CG14943 Protein, Dmel_CG14944 Protein, Dmel_CG31757 Protein, Dmel_CG31758 Protein, Dmel_CG42325 Protein, PDE1C Protein, PDE1c Protein, GB13690 Protein, Hcam3 Protein, Phosphodiesterase 1c Protein, phosphodiesterase 1C Protein, calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A Protein, calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C Protein, phosphodiesterase 1C, calmodulin-dependent b Protein, Pde1c Protein, PDE1C Protein, LOC724389 Protein, LOC100019026 Protein, pde1cb Protein
- Background
- This gene encodes an enzyme that belongs to the 3'5'-cyclic nucleotide phosphodiesterase family. Members of this family catalyze hydrolysis of the cyclic nucleotides, cyclic adenosine monophosphate and cyclic guanosine monophosphate, to the corresponding nucleoside 5'-monophosphates. The enzyme encoded by this gene regulates proliferation and migration of vascular smooth muscle cells, and neointimal hyperplasia. This enzyme also plays a role in pathological vascular remodeling by regulating the stability of growth factor receptors, such as PDGF-receptor-beta.
- Molecular Weight
- 72 kDa
- NCBI Accession
- NP_005011
- Pathways
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Negative Regulation of Hormone Secretion, cAMP Metabolic Process, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma
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