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PDE4B Protein (Transcript Variant D) (Myc-DYKDDDDK Tag)

PDE4B Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2728514
  • Target See all PDE4B Proteins
    PDE4B (phosphodiesterase 4B, cAMP-Specific (PDE4B))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant D
    Origin
    • 5
    • 2
    • 1
    Human
    Source
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This PDE4B protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human PDE4B (transcript variant d) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product PDE4B Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    PDE4B (phosphodiesterase 4B, cAMP-Specific (PDE4B))
    Alternative Name
    Pde4b (PDE4B Products)
    Synonyms
    dpde4 Protein, pde4b5 Protein, pdeivb Protein, Dpde4 Protein, R74983 Protein, dunce Protein, PDE4/IVb Protein, Pde4B1 Protein, Pde4B2 Protein, Pde4B3 Protein, Pde4B4 Protein, DPDE4 Protein, PDE4B5 Protein, PDEIVB Protein, phosphodiesterase 4B Protein, phosphodiesterase 4B, cAMP specific Protein, phosphodiesterase 4B S homeolog Protein, pde4b Protein, PDE4B Protein, Pde4b Protein, pde4b.S Protein
    Background
    This gene is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms.
    Molecular Weight
    83.2 kDa
    NCBI Accession
    NP_001032418
    Pathways
    Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction
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