PDHA1 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2728547

Product Details

Target: PDHA1 (Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This PDHA1 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human PDHA1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: PDHA1 (Pyruvate Dehydrogenase (Lipoamide) alpha 1 (PDHA1))

Alternative Name: Pdha1 (PDHA1 Products)

Synonyms: PDHA Protein, PDHCE1A Protein, PHE1A Protein, Pdha-1 Protein, pdha Protein, phe1a Protein, pdhce1a Protein, im:6895726 Protein, pdha1 Protein, wu:fd18b01 Protein, wu:fo96f03 Protein, zgc:73271 Protein, zgc:86692 Protein, Pdha1 Protein, wu:fp73b04 Protein, zgc:92705 Protein, NI36_05250 Protein, pdha1-a Protein, pdha1-b Protein, pyruvate dehydrogenase E1 alpha 1 subunit Protein, pyruvate dehydrogenase E1 alpha 1 Protein, pyruvate dehydrogenase (lipoamide) alpha 1 Protein, pyruvate dehydrogenase (lipoamide) alpha 1 pseudogene Protein, 2-oxo acid dehydrogenase Protein, pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha Protein, pyruvate dehydrogenase alpha subunit protein Protein, pyruvate dehydrogenase (acetyl-transferring) protein, alpha subunit Protein, precursor of dehydrogenase pyruvate dehydrogenase E1 component alpha subunit Protein, pyruvate dehydrogenase Protein, pyruvate dehydrogenase E1 alpha 1 subunit a Protein, pyruvate dehydrogenase E1 alpha 1 subunit b Protein, pyruvate dehydrogenase E1 component subunit alpha Protein, pyruvate dehydrogenase (lipoamide) alpha 1 S homeolog Protein, PDHA1 Protein, Pdha1 Protein, pdha1 Protein, LOC719277 Protein, VNG_RS07485 Protein, RR_RS04695 Protein, pdhA1 Protein, pdha1a Protein, pdha1b Protein, NI36_RS05240 Protein, pdha1.S Protein

Background: The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2010]

Molecular Weight: 40.2 kDa

NCBI Accession: NP_000275

Pathways: Warburg Effect