PDZ and LIM Domain 2 (Mystique) (PDLIM2) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)

Details for Product No. ABIN2728589, Supplier: Log in to see
Protein Name
  • 4732462F18Rik
  • Slim
  • MYSTIQUE
  • SLIM
  • PDZ and LIM domain 2
  • Pdlim2
  • PDLIM2
Protein Characteristics
Transcript Variant 2
3
1
1
1
1
Origin
Human
3
1
1
1
Source
HEK-293 Cells
2
2
1
1
Protein Type
Recombinant
Purification tag / Conjugate
This PDLIM2 protein is labelled with Myc-DYKDDDDK Tag.
Application
Antibody Production (AbP), Functional Studies (Func), Protein Interaction (PI), Standard (STD)
Options
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Specificity Optimal preservation of protein structure, post-translational modifications and functions.
Characteristics
  • Recombinant human PDLIM2 (transcript variant 2) protein expressed in HEK293 cells.
  • Produced with end-sequenced ORF clone
Purity > 80 % as determined by SDS-PAGE and Coomassie blue staining
Background This gene encodes a member of the ALP subfamily of PDZ-LIM domain proteins. The encoded protein suppresses anchorage-dependent growth and promotes cell migration and adhesion through interactions with the actin cytoskeleton via the PDZ domain. The encoded protein is also a putative tumor suppressor protein, and decreased expression of this gene is associated with several malignancies including breast cancer and adult T-cell leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Molecular Weight 37.3 kDa
NCBI Accession NP_067643
Application Notes Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays
Protein-protein interaction
In vitro biochemical assays and cell-based functional assays
Comment

The tag is located at the C-terminal.

Restrictions For Research Use only
Concentration > 50 μg/mL
Buffer 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
Storage -80 °C
Storage Comment Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
Supplier Images
Western Blotting (WB) image for PDZ and LIM Domain 2 (Mystique) (PDLIM2) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag) (ABIN2728589) Validation with Western Blot
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