PEX19 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2728692

Product Details

Target: PEX19 (Peroxisomal Biogenesis Factor 19 (PEX19))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 1

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This PEX19 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human Peroxin 19 / PEX19 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: PEX19 (Peroxisomal Biogenesis Factor 19 (PEX19))

Alternative Name: Peroxin 19,pex19 (PEX19 Products)

Synonyms: BEST:GH03076 Protein, CG5325 Protein, DmelPex19 Protein, Dmel\\CG5325 Protein, D1S2223E Protein, HK33 Protein, PBD12A Protein, PMP1 Protein, PMPI Protein, PXF Protein, PXMP1 Protein, Pxf Protein, PxF Protein, Peroxin-19 Protein, Peroxin 19 Protein, Peroxisomal farnesylated protein Protein, peroxisomal biogenesis factor 19 Protein, Pex19 Protein, Bm1_19905 Protein, PEX19 Protein

Background: This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants.

Molecular Weight: 32.6 kDa

NCBI Accession: NP_002848