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PHGDH Protein (His tag)

PHGDH Origin: Human Host: Insect cells (Sf9) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2728836
  • Target See all PHGDH Proteins
    PHGDH (phosphoglycerate Dehydrogenase (PHGDH))
    Protein Type
    Recombinant
    Origin
    • 6
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Source
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Insect cells (Sf9)
    Purification tag / Conjugate
    This PHGDH protein is labelled with His tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human PHGDH (full length, N-term HIS tag) protein expressed in Sf9 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product PHGDH Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the N-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    50 mM Tris-HCl, pH 8.0, 100 mM glycine, 10 % glycerol. Store at -80C. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    PHGDH (phosphoglycerate Dehydrogenase (PHGDH))
    Alternative Name
    Phgdh (PHGDH Products)
    Synonyms
    fb38f06 Protein, zgc:65956 Protein, wu:fb38f06 Protein, embryo sac development arrest 9 Protein, F10M10.7 Protein, ECK2909 Protein, JW2880 Protein, 3-PGDH Protein, 3PGDH Protein, 4930479N23 Protein, A10 Protein, PGAD Protein, PGD Protein, PGDH Protein, SERA Protein, PDG Protein, phosphoglycerate dehydrogenase Protein, D-3-phosphoglycerate dehydrogenase Protein, 3-phosphoglycerate dehydrogenase Protein, phgdh Protein, EDA9 Protein, serA Protein, Sthe_2284 Protein, Dacet_1260 Protein, Mrub_0173 Protein, MMAH_RS07650 Protein, Arnit_0487 Protein, Ndas_0174 Protein, Mesil_2386 Protein, Slip_0010 Protein, Trad_0302 Protein, Acear_0027 Protein, Mahau_0665 Protein, MZHIL_RS05165 Protein, Mesop_1331 Protein, Thein_0855 Protein, Phgdh Protein, PHGDH Protein
    Background
    This gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known.
    Molecular Weight
    56.7 kDa
    NCBI Accession
    NP_006614
    Pathways
    Metabolism of Steroid Hormones and Vitamin D, Warburg Effect
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