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PLA2G1B Protein (Myc-DYKDDDDK Tag)

PLA2G1B Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2729073
  • Target See all PLA2G1B Proteins
    PLA2G1B (Phospholipase A2, Group IB (PLA2G1B))
    Protein Type
    Recombinant
    Origin
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    Human
    Source
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    HEK-293 Cells
    Purification tag / Conjugate
    This PLA2G1B protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human PLA2G1B protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product PLA2G1B Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    PLA2G1B (Phospholipase A2, Group IB (PLA2G1B))
    Alternative Name
    Pla2g1b (PLA2G1B Products)
    Synonyms
    C133 Protein, CG4346 Protein, Dmel\\CG42237 Protein, Dmel_CG4346 Protein, PLA2 Protein, GB13351 Protein, bvPLA2 Protein, PLA2A Protein, PPLA2 Protein, sPLA(2)-IB Protein, Pla2a Protein, sPLA2IB Protein, PLA2G1B Protein, CG42237 gene product from transcript CG42237-RB Protein, phospholipase A2 Protein, phospholipase A2 group IB Protein, phospholipase A2, group IB, pancreas Protein, phospholipase A2 group IVA Protein, CG42237 Protein, PLA2 Protein, LOC100631065 Protein, Pla2 Protein, PLA2G1B Protein, Pla2g1b Protein, PLA2G4A Protein
    Background
    This gene encodes a secreted member of the phospholipase A2 (PLA2) class of enzymes, which is produced by the pancreatic acinar cells. The encoded calcium-dependent enzyme catalyzes the hydrolysis of the sn-2 position of membrane glycerophospholipids to release arachidonic acid (AA) and lysophospholipids. AA is subsequently converted by downstream metabolic enzymes to several bioactive lipophilic compounds (eicosanoids), including prostaglandins (PGs) and leukotrienes (LTs). The enzyme may be involved in several physiological processes including cell contraction, cell proliferation and pathological response.
    Molecular Weight
    16.2 kDa
    NCBI Accession
    NP_000919
    Pathways
    Inositol Metabolic Process, VEGF Signaling
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