PPP1R13B Protein (Myc-DYKDDDDK Tag)
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- Target See all PPP1R13B Proteins
- PPP1R13B (Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PPP1R13B protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human PPP1R13B protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PPP1R13B Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- PPP1R13B (Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B))
- Alternative Name
- Ppp1r13b (PPP1R13B Products)
- Synonyms
- ASPP1 Protein, p53BP2-like Protein, p85 Protein, AI449786 Protein, AW545810 Protein, Tp53bp2 Protein, Trp53bp2 Protein, protein phosphatase 1 regulatory subunit 13B Protein, protein phosphatase 1, regulatory subunit 13B Protein, protein phosphatase 1 regulatory subunit 13B L homeolog Protein, protein phosphatase 1, regulatory subunit 13Bb Protein, protein phosphatase 1, regulatory (inhibitor) subunit 13B Protein, PPP1R13B Protein, Ppp1r13b Protein, ppp1r13b.L Protein, ppp1r13bb Protein, ppp1r13b Protein
- Background
- This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor.
- Molecular Weight
- 119.4 kDa
- NCBI Accession
- NP_056131
- Pathways
- p53 Signaling
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