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PPP1R13B Protein (Myc-DYKDDDDK Tag)

PPP1R13B Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2729471
  • Target See all PPP1R13B Proteins
    PPP1R13B (Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B))
    Protein Type
    Recombinant
    Origin
    • 2
    • 1
    Human
    Source
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This PPP1R13B protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human PPP1R13B protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product PPP1R13B Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    PPP1R13B (Protein Phosphatase 1, Regulatory Subunit 13B (PPP1R13B))
    Alternative Name
    Ppp1r13b (PPP1R13B Products)
    Synonyms
    ASPP1 Protein, p53BP2-like Protein, p85 Protein, AI449786 Protein, AW545810 Protein, Tp53bp2 Protein, Trp53bp2 Protein, protein phosphatase 1 regulatory subunit 13B Protein, protein phosphatase 1, regulatory subunit 13B Protein, protein phosphatase 1 regulatory subunit 13B L homeolog Protein, protein phosphatase 1, regulatory subunit 13Bb Protein, protein phosphatase 1, regulatory (inhibitor) subunit 13B Protein, PPP1R13B Protein, Ppp1r13b Protein, ppp1r13b.L Protein, ppp1r13bb Protein, ppp1r13b Protein
    Background
    This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor.
    Molecular Weight
    119.4 kDa
    NCBI Accession
    NP_056131
    Pathways
    p53 Signaling
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