PRAM1 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2729546

Product Details

Target: PRAM1 (PML-RARA Regulated Adaptor Molecule 1 (PRAM1))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This PRAM1 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human PRAM1 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: PRAM1 (PML-RARA Regulated Adaptor Molecule 1 (PRAM1))

Alternative Name: Pram1 (PRAM1 Products)

Synonyms: PRAM1 Protein, AY665714 Protein, PML-RAR Protein, PRAM-1 Protein, RGD1564330 Protein, PML-RARA regulated adaptor molecule 1 Protein, PML-RAR alpha-regulated adaptor molecule 1 Protein, PRAM1 Protein, Pram1 Protein

Background: The protein encoded by this gene is similar to FYN binding protein (FYB/SLAP-130), an adaptor protein involved in T cell receptor mediated signaling. This gene is expressed and regulated during normal myelopoiesis. The expression of this gene is induced by retinoic acid and is inhibited by the expression of PML-RARalpha, a fusion protein of promyelocytic leukemia (PML) and the retinoic acid receptor-alpha (RARalpha).

Molecular Weight: 73.7 kDa

NCBI Accession: NP_115528

Pathways: Regulation of Leukocyte Mediated Immunity