PRKAR1B Protein (Transcript Variant 5) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2729590

Product Details

Target: PRKAR1B (Protein Kinase, CAMP-Dependent, Regulatory, Type I, beta (PRKAR1B))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 5

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This PRKAR1B protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human PRKAR1B (transcript variant 5) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: PRKAR1B (Protein Kinase, CAMP-Dependent, Regulatory, Type I, beta (PRKAR1B))

Alternative Name: Prkar1b (PRKAR1B Products)

Synonyms: PRKAR1B Protein, AI385716 Protein, RIbeta Protein, RGD1563094 Protein, PRKAR1 Protein, zgc:153624 Protein, prkar1 Protein, protein kinase cAMP-dependent type I regulatory subunit beta Protein, protein kinase, cAMP dependent regulatory, type I beta Protein, protein kinase cAMP-dependent type 1 regulatory subunit beta Protein, protein kinase, cAMP-dependent, regulatory, type I, beta Protein, protein kinase, cAMP-dependent, regulatory subunit type I beta S homeolog Protein, PRKAR1B Protein, prkar1b Protein, Prkar1b Protein, prkar1b.S Protein

Background: The protein encoded by this gene is a regulatory subunit of cyclic AMP-dependent protein kinase A (PKA), which is involved in the signaling pathway of the second messenger cAMP. Two regulatory and two catalytic subunits form the PKA holoenzyme, disbands after cAMP binding. The holoenzyme is involved in many cellular events, including ion transport, metabolism, and transcription. Several transcript variants encoding the same protein have been found for this gene.

Molecular Weight: 42.9 kDa

NCBI Accession: NP_001158232

Pathways: Hedgehog Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, G-protein mediated Events, Interaction of EGFR with phospholipase C-gamma