PKC delta Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2729605

Product Details

Target: PKC delta (PKCd) (Protein Kinase C, delta (PKCd))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 2

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This PKC delta protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human PRKCD (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: PKC delta (PKCd) (Protein Kinase C, delta (PKCd))

Alternative Name: Prkcd (PKCd Products)

Synonyms: MAY1 Protein, PKCD Protein, nPKC-delta Protein, AI385711 Protein, D14Ertd420e Protein, PKC[d] Protein, PKCdelta Protein, Pkcd Protein, fb09d10 Protein, fv43b11 Protein, prkcd Protein, wu:fb09d10 Protein, wu:fv43b11 Protein, zgc:56558 Protein, PKC-delta Protein, may1 Protein, npkc-delta Protein, pkc-delta2 Protein, pkcd Protein, tpa-1 Protein, protein kinase C delta Protein, protein kinase C, delta Protein, protein kinase C, delta a Protein, protein kinase C delta L homeolog Protein, PRKCD Protein, Prkcd Protein, prkcda Protein, prkcd.L Protein, prkcd Protein

Background: Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. Alternatively spliced transcript variants encoding the same protein have been observed.

Molecular Weight: 77.3 kDa

NCBI Accession: NP_997704

Pathways: Interferon-gamma Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Myometrial Relaxation and Contraction, M Phase, G-protein mediated Events, Dicarboxylic Acid Transport, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, Lipid Metabolism