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PKC gamma Protein (Myc-DYKDDDDK Tag)

PRKCG Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2729627
  • Target See all PKC gamma (PRKCG) Proteins
    PKC gamma (PRKCG) (Protein Kinase C, gamma (PRKCG))
    Protein Type
    Recombinant
    Origin
    • 5
    • 3
    • 1
    Human
    Source
    • 3
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This PKC gamma protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human PRKCG protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product PRKCG Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    PKC gamma (PRKCG) (Protein Kinase C, gamma (PRKCG))
    Alternative Name
    Prkcg (PRKCG Products)
    Synonyms
    PRKCG Protein, PKC-gamma Protein, PKCC Protein, PKCG Protein, SCA14 Protein, PKCgamma Protein, Pkcc Protein, Prkcc Protein, PKC Protein, PKCI Protein, Prkc Protein, RATPKCI Protein, protein kinase C gamma Protein, protein kinase C, gamma Protein, protein kinase C gamma type Protein, PRKCG Protein, Prkcg Protein, LOC484316 Protein
    Background
    Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions, including long term potentiation (LTP) and long term depression (LTD), specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14). Two transcript variants encoding different isoforms have been found for this gene.
    Molecular Weight
    78.3 kDa
    NCBI Accession
    NP_002730
    Pathways
    WNT Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Thyroid Hormone Synthesis, Myometrial Relaxation and Contraction, G-protein mediated Events, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, VEGF Signaling
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