Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

PKC iota Protein (Myc-DYKDDDDK Tag)

PRKCI Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2729628
  • Target See all PKC iota (PRKCI) Proteins
    PKC iota (PRKCI) (Protein Kinase C, iota (PRKCI))
    Protein Type
    Recombinant
    Origin
    • 7
    • 1
    • 1
    Human
    Source
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This PKC iota protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human PRKCI protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product PRKCI Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    PKC iota (PRKCI) (Protein Kinase C, iota (PRKCI))
    Alternative Name
    Prkci (PRKCI Products)
    Synonyms
    DXS1179E Protein, PKCI Protein, nPKC-iota Protein, aPKC[l] Protein, hal Protein, has Protein, PRKCI Protein, PKC Protein, 2310021H13Rik Protein, AI427505 Protein, PKClambda Protein, Pkci Protein, Pkcl Protein, Prkcl Protein, aPKClambda Protein, mKIAA4165 Protein, protein kinase C iota Protein, protein kinase C, iota Protein, PRKCI Protein, prkci Protein, Prkci Protein
    Background
    This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases. The PKC family comprises at least eight members, which are differentially expressed and are involved in a wide variety of cellular processes. This protein kinase is calcium-independent and phospholipid-dependent. It is not activated by phorbolesters or diacylglycerol. This kinase can be recruited to vesicle tubular clusters (VTCs) by direct interaction with the small GTPase RAB2, where this kinase phosphorylates glyceraldehyde-3-phosphate dehydrogenase (GAPD/GAPDH) and plays a role in microtubule dynamics in the early secretory pathway. This kinase is found to be necessary for BCL-ABL-mediated resistance to drug-induced apoptosis and therefore protects leukemia cells against drug-induced apoptosis. There is a single exon pseudogene mapped on chromosome X.
    Molecular Weight
    68.1 kDa
    NCBI Accession
    NP_002731
    Pathways
    Neurotrophin Signaling Pathway, Cell-Cell Junction Organization, Tube Formation
You are here:
Support