PRKAG1 Protein (Catalytic Subunit, Transcript Variant 2) (Myc-DYKDDDDK Tag)
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- Target See all PRKAG1 Proteins
- PRKAG1 (Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1))
- Protein Type
- Recombinant
- Protein Characteristics
- Catalytic Subunit, Transcript Variant 2
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This PRKAG1 protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human Protein kinase, AMP-activated, gamma 1 non-catalytic subunit (PRKAG1), transcript variant 2 (transcript variant 2) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product PRKAG1 Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- PRKAG1 (Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1))
- Abstract
- PRKAG1 Products
- Synonyms
- MGC68503 Protein, zgc:63896 Protein, wu:fa94d09 Protein, wu:fd12h04 Protein, AMPKG Protein, Prkaac Protein, Prkga1 Protein, AA571379 Protein, BB036179 Protein, protein kinase, AMP-activated, gamma 1 non-catalytic subunit S homeolog Protein, protein kinase, AMP-activated, gamma 1 non-catalytic subunit Protein, protein kinase AMP-activated non-catalytic subunit gamma 1 Protein, prkag1.S Protein, prkag1 Protein, PRKAG1 Protein, Prkag1 Protein
- Background
- The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
- Molecular Weight
- 28.1 kDa
- NCBI Accession
- NP_997626
- Pathways
- AMPK Signaling, Regulation of Carbohydrate Metabolic Process, Warburg Effect
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