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PRKAG1 Protein (Catalytic Subunit, Transcript Variant 2) (Myc-DYKDDDDK Tag)

PRKAG1 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2729786
  • Target See all PRKAG1 Proteins
    PRKAG1 (Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1))
    Protein Type
    Recombinant
    Protein Characteristics
    Catalytic Subunit, Transcript Variant 2
    Origin
    • 3
    • 1
    • 1
    Human
    Source
    • 3
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This PRKAG1 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Protein kinase, AMP-activated, gamma 1 non-catalytic subunit (PRKAG1), transcript variant 2 (transcript variant 2) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product PRKAG1 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    PRKAG1 (Protein Kinase, AMP-Activated, gamma 1 Non-Catalytic Subunit (PRKAG1))
    Abstract
    PRKAG1 Products
    Synonyms
    MGC68503 Protein, zgc:63896 Protein, wu:fa94d09 Protein, wu:fd12h04 Protein, AMPKG Protein, Prkaac Protein, Prkga1 Protein, AA571379 Protein, BB036179 Protein, protein kinase, AMP-activated, gamma 1 non-catalytic subunit S homeolog Protein, protein kinase, AMP-activated, gamma 1 non-catalytic subunit Protein, protein kinase AMP-activated non-catalytic subunit gamma 1 Protein, prkag1.S Protein, prkag1 Protein, PRKAG1 Protein, Prkag1 Protein
    Background
    The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
    Molecular Weight
    28.1 kDa
    NCBI Accession
    NP_997626
    Pathways
    AMPK Signaling, Regulation of Carbohydrate Metabolic Process, Warburg Effect
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