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PPM1L Protein (Myc-DYKDDDDK Tag)

PPM1L Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2729816
  • Target See all PPM1L Proteins
    PPM1L (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1L (PPM1L))
    Protein Type
    Recombinant
    Origin
    • 3
    • 2
    Human
    Source
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This PPM1L protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human Protein phosphatase 1L / PPM1L protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product PPM1L Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    PPM1L (Protein Phosphatase, Mg2+/Mn2+ Dependent, 1L (PPM1L))
    Alternative Name
    Protein Phosphatase 1l,ppm1l (PPM1L Products)
    Synonyms
    3222401G13 Protein, 5930404J21Rik Protein, AI481720 Protein, AW045850 Protein, PP2C Protein, PP2Cepsilon Protein, Pp2ce Protein, Ppp2ce Protein, mKIAA4175 Protein, PP2C-epsilon Protein, PP2CE Protein, PPM1-LIKE Protein, ppm1l Protein, zgc:153235 Protein, zgc:154091 Protein, protein phosphatase 1 (formerly 2C)-like Protein, protein phosphatase, Mg2+/Mn2+ dependent, 1L Protein, protein phosphatase, Mg2+/Mn2+ dependent 1L Protein, protein phosphatase, Mg2+/Mn2+ dependent 1L L homeolog Protein, protein phosphatase, Mg2+/Mn2+ dependent, 1Lb Protein, protein phosphatase, Mg2+/Mn2+ dependent, 1La Protein, Ppm1l Protein, PPM1L Protein, ppm1l.L Protein, ppm1lb Protein, ppm1la Protein
    Background
    The protein encoded by this gene is a magnesium or manganese-requiring phosphatase that is involved in several signaling pathways. The encoded protein downregulates apoptosis signal-regulating kinase 1, a protein that initiates a signaling cascade that leads to apoptosis when cells are subjected to cytotoxic stresses. This protein also is an endoplasmic reticulum transmembrane protein that helps regulate ceramide transport from the endoplasmic reticulum to the Golgi apparatus. Finally, this gene may be involved in adiposity since it is upregulated in adipose tissues. Several transcript variants encoding different isoforms have been found for this gene.
    Molecular Weight
    40.9 kDa
    NCBI Accession
    NP_640338
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