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Prostaglandin E Synthase Protein (PTGES) (Myc-DYKDDDDK Tag)

PTGES Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2730064
  • Target See all Prostaglandin E Synthase (PTGES) Proteins
    Prostaglandin E Synthase (PTGES)
    Protein Type
    Recombinant
    Origin
    • 4
    • 2
    • 1
    Human
    Source
    • 3
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This Prostaglandin E Synthase protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human PTGES protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product PTGES Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    Prostaglandin E Synthase (PTGES)
    Alternative Name
    Ptges (PTGES Products)
    Synonyms
    ptges Protein, MGC80290 Protein, PTGES Protein, MGST-IV Protein, MGST1-L1 Protein, MGST1L1 Protein, MPGES Protein, PGES Protein, PIG12 Protein, PP102 Protein, PP1294 Protein, TP53I12 Protein, mPGES-1 Protein, 2410099E23Rik Protein, D2Ertd369e Protein, Pges Protein, mPGES Protein, MPGES-1 Protein, prostaglandin E synthase Protein, prostaglandin E synthase S homeolog Protein, PTGES Protein, ptges.S Protein, Ptges Protein
    Background
    The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses.
    Molecular Weight
    16.9 kDa
    NCBI Accession
    NP_004869
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