PTP4A2 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2730095

Product Details

Target: PTP4A2 (Protein tyrosine Phosphatase Type IVA, Member 2 (PTP4A2))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 1

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This PTP4A2 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human PTP4A2 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: PTP4A2 (Protein tyrosine Phosphatase Type IVA, Member 2 (PTP4A2))

Alternative Name: Ptp4a2 (PTP4A2 Products)

Synonyms: wu:fc05f09 Protein, wu:fi84b06 Protein, zgc:101724 Protein, MGC53390 Protein, MGC80084 Protein, MGC132077 Protein, PTP4A2 Protein, ptp4a2 Protein, Prl-2 Protein, HH13 Protein, HH7-2 Protein, HU-PP-1 Protein, OV-1 Protein, PRL-2 Protein, PRL2 Protein, PTP4A Protein, PTPCAAX2 Protein, ptp-IV1a Protein, ptp-IV1b Protein, protein tyrosine phosphatase type IVA, member 2b Protein, protein tyrosine phosphatase 4a2 Protein, protein tyrosine phosphatase type IVA, member 2 Protein, protein tyrosine phosphatase type IVA, member 2 L homeolog Protein, ptp4a2b Protein, ptp4a2 Protein, PTP4A2 Protein, ptp4a2.L Protein, Ptp4a2 Protein

Background: The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17.

Molecular Weight: 18.9 kDa

NCBI Accession: NP_536316