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PTPRO Protein (Transcript Variant 5) (Myc-DYKDDDDK Tag)

PTPRO Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2730149
  • Target See all PTPRO Proteins
    PTPRO (Protein tyrosine Phosphatase, Receptor Type, O (PTPRO))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 5
    Origin
    • 7
    • 4
    Human
    Source
    • 6
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This PTPRO protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human PTPRO (transcript variant 5) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product PTPRO Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    PTPRO (Protein tyrosine Phosphatase, Receptor Type, O (PTPRO))
    Alternative Name
    Ptpro (PTPRO Products)
    Synonyms
    GLEPP1 Protein, RPTP-BK Protein, D28 Protein, PTPBK Protein, PTPROt Protein, PTPU2 Protein, PTPoc Protein, PTPphi Protein, Ptpn15 Protein, R-PTP-O Protein, NPHS6 Protein, PTP-OC Protein, PTP-U2 Protein, PTPROT Protein, protein tyrosine phosphatase, receptor type O Protein, protein tyrosine phosphatase, receptor type, O Protein, PTPRO Protein, Ptpro Protein
    Background
    This gene encodes a member of the R3 subtype family of receptor-type protein tyrosine phosphatases. These proteins are localized to the apical surface of polarized cells and may have tissue-specific functions through activation of Src family kinases. This gene contains two distinct promoters, and alternatively spliced transcript variants encoding multiple isoforms have been observed. The encoded proteins may have multiple isoform-specific and tissue-specific functions, including the regulation of osteoclast production and activity, inhibition of cell proliferation and facilitation of apoptosis. This gene is a candidate tumor suppressor, and decreased expression of this gene has been observed in several types of cancer.
    Molecular Weight
    47 kDa
    NCBI Accession
    NP_109596
    Pathways
    Cell-Cell Junction Organization
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