PTPRS Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2730154

Product Details

Target: PTPRS (Protein tyrosine Phosphatase, Receptor Type, S (PTPRS))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 2

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This PTPRS protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human PTPRS (transcript variant 2) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: PTPRS (Protein tyrosine Phosphatase, Receptor Type, S (PTPRS))

Alternative Name: Ptprs (PTPRS Products)

Synonyms: PTPSIGMA Protein, AL022616 Protein, PTP Protein, PTP-NU3 Protein, PTPNU-3 Protein, PTPsigma Protein, Ptpt9 Protein, R-PTP-S Protein, RPTPsigma Protein, Larptp2 Protein, Ptprd Protein, Ptpsigma Protein, Ptpsigma. Protein, Rptpd Protein, protein tyrosine phosphatase, receptor type S Protein, protein tyrosine phosphatase, receptor type, S Protein, PTPRS Protein, Ptprs Protein

Background: The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of multiple Ig-like and fibronectin type III-like domains. Studies of the similar gene in mice suggested that this PTP may be involved in cell-cell interaction, primary axonogenesis, and axon guidance during embryogenesis. This PTP has been also implicated in the molecular control of adult nerve repair. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported.

Molecular Weight: 209.7 kDa

NCBI Accession: NP_570924