QPRT Protein (Myc-DYKDDDDK Tag)
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- Target See all QPRT Proteins
- QPRT (Quinolinate Phosphoribosyltransferase (QPRT))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This QPRT protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human QPRT protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product QPRT Protein
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Quinolinate Phosphoribosyltransferase (QPRT) (AA 1-297) protein (His tag)
QPRT Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Quinolinate Phosphoribosyltransferase (QPRT) (AA 1-297) protein (GST tag)QPRT Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Quinolinate Phosphoribosyltransferase (QPRT) (AA 198-297) protein (GST tag)QPRT Origin: Human Host: Wheat germ Recombinant ELISA, WB, AP, AA
Quinolinate Phosphoribosyltransferase (QPRT) (AA 1-297) protein (Strep Tag)Crystallography grade QPRT Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Quinolinate Phosphoribosyltransferase (QPRT) (AA 1-299) protein (Strep Tag)Crystallography grade QPRT Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- QPRT (Quinolinate Phosphoribosyltransferase (QPRT))
- Alternative Name
- Qprt (QPRT Products)
- Synonyms
- ECK0108 Protein, JW0105 Protein, VF2184 Protein, QPRTase Protein, 2410027J01Rik Protein, AI647766 Protein, quinolinate phosphoribosyltransferase Protein, nicotinate-nucleotide pyrophosphorylase Protein, nicotinate-nucleotide diphosphorylase Protein, carboxylating Protein, ECs0113 Protein, nadC Protein, VP2522 Protein, STY0167 Protein, BJE04_RS13210 Protein, QPRT Protein, Qprt Protein
- Background
- This gene encodes a key enzyme in catabolism of quinolinate, an intermediate in the tryptophan-nicotinamide adenine dinucleotide pathway. Quinolinate acts as a most potent endogenous exitotoxin to neurons. Elevation of quinolinate levels in the brain has been linked to the pathogenesis of neurodegenerative disorders such as epilepsy, Alzheimer's disease, and Huntington's disease. Alternative splicing results in multiple transcript variants.
- Molecular Weight
- 30.6 kDa
- NCBI Accession
- NP_055113
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