RAD51C Protein (His tag)

Catalog No. ABIN2730411

Product Details

Target: RAD51C (DNA Repair Protein RAD51 Homolog 3 (RAD51C))

Protein Type: Recombinant

Origin: Human

Source: Escherichia coli (E. coli)

Purification tag / Conjugate: This RAD51C protein is labelled with His tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human RAD51C (full length, N-term HIS tag, transcript variant 2) protein expressed in E. coli.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the N-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris, pH 8.0, 150 mM NaCl, 10 % glycerol, 1 % Sarkosyl.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: RAD51C (DNA Repair Protein RAD51 Homolog 3 (RAD51C))

Alternative Name: Rad51c (RAD51C Products)

Synonyms: RGD1563765 Protein, CG2412 Protein, Dm CG2412 Protein, Dmel\\CG2412 Protein, zgc:101596 Protein, RAD51C Protein, Rad51c Protein, ATRAD51C Protein, F4L23.21 Protein, RAS associated with diabetes protein 51C Protein, R51H3 Protein, Rad51l2 Protein, BROVCA3 Protein, FANCO Protein, RAD51L2 Protein, RAD51 paralog C Protein, Rad51 recombinase D Protein, Rad51 DNA recombinase 3 Protein, RAD51C protein Protein, RAD51 homolog C Protein, RAS associated with diabetes protein 51C Protein, RAD51C Protein, Rad51c Protein, Rad51D Protein, rad51c Protein

Background: This gene is a member of the RAD51 family. RAD51 family members are highly similar to bacterial RecA and Saccharomyces cerevisiae Rad51 and are known to be involved in the homologous recombination and repair of DNA. This protein can interact with other RAD51 paralogs and is reported to be important for Holliday junction resolution. Mutations in this gene are associated with Fanconi anemia-like syndrome. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing results in multiple transcript variants.

Molecular Weight: 14.7 kDa

NCBI Accession: NP_002867

Pathways: DNA Damage Repair