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RAD51 Homolog B Protein (Rad51B) (His tag)

Rad51B Origin: Human Host: Escherichia coli (E. coli) Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2730413
  • Target See all RAD51 Homolog B (Rad51B) Proteins
    RAD51 Homolog B (Rad51B)
    Protein Type
    Recombinant
    Origin
    • 3
    • 1
    • 1
    Human
    Source
    • 2
    • 1
    • 1
    • 1
    Escherichia coli (E. coli)
    Purification tag / Conjugate
    This RAD51 Homolog B protein is labelled with His tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human RAD51L1 (N-term HIS tag, transcript variant 3) protein expressed in E. coli.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product Rad51B Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the N-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    50 mM Tris,8M Urea, pH 8.0.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    RAD51 Homolog B (Rad51B)
    Alternative Name
    Rad51l1 (Rad51B Products)
    Synonyms
    R51H2 Protein, RAD51L1 Protein, REC2 Protein, AI553500 Protein, Rad51l1 Protein, mREC2 Protein, ATRAD51B Protein, T17D12.12 Protein, T17D12_12 Protein, RGD1560681 Protein, rad51l1 Protein, wu:fd07f04 Protein, zgc:56581 Protein, RAD51 paralog B Protein, DNA repair (Rad51) family protein Protein, Rad51 DNA recombinase 2 Protein, RAD51B Protein, Rad51b Protein, rad51b Protein
    Background
    The protein encoded by this gene is a member of the RAD51 protein family. RAD51 family members are evolutionarily conserved proteins essential for DNA repair by homologous recombination. This protein has been shown to form a stable heterodimer with the family member RAD51C, which further interacts with the other family members, such as RAD51, XRCC2, and XRCC3. Overexpression of this gene was found to cause cell cycle G1 delay and cell apoptosis, which suggested a role of this protein in sensing DNA damage. Rearrangements between this locus and high mobility group AT-hook 2 (HMGA2, GeneID 8091) have been observed in uterine leiomyomata.
    Molecular Weight
    42 kDa
    NCBI Accession
    NP_598193
    Pathways
    DNA Damage Repair
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