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RAD9A Protein (Myc-DYKDDDDK Tag)

RAD9A Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2730420
  • Target See all RAD9A Proteins
    RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))
    Protein Type
    Recombinant
    Origin
    • 2
    • 1
    • 1
    Human
    Source
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This RAD9A protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human RAD9A protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product RAD9A Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))
    Alternative Name
    Rad9a (RAD9A Products)
    Synonyms
    RAD9 Protein, Rad9 Protein, rad9a Protein, MGC89062 Protein, XRad9 Protein, rad9 Protein, RAD9 checkpoint clamp component A Protein, RAD9 checkpoint clamp component B Protein, RAD9 checkpoint clamp component A L homeolog Protein, RAD9A Protein, Rad9a Protein, rad9a Protein, rad9b Protein, rad9a.L Protein
    Background
    This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair. This protein possesses 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    Molecular Weight
    42.4 kDa
    NCBI Accession
    NP_004575
    Pathways
    Positive Regulation of Response to DNA Damage Stimulus
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