RAD9A Protein (Myc-DYKDDDDK Tag)
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- Target See all RAD9A Proteins
- RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This RAD9A protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human RAD9A protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product RAD9A Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- RAD9A (RAD9 Homolog A (S. Pombe) (RAD9A))
- Alternative Name
- Rad9a (RAD9A Products)
- Synonyms
- RAD9 Protein, Rad9 Protein, rad9a Protein, MGC89062 Protein, XRad9 Protein, rad9 Protein, RAD9 checkpoint clamp component A Protein, RAD9 checkpoint clamp component B Protein, RAD9 checkpoint clamp component A L homeolog Protein, RAD9A Protein, Rad9a Protein, rad9a Protein, rad9b Protein, rad9a.L Protein
- Background
- This gene product is highly similar to Schizosaccharomyces pombe rad9, a cell cycle checkpoint protein required for cell cycle arrest and DNA damage repair. This protein possesses 3' to 5' exonuclease activity, which may contribute to its role in sensing and repairing DNA damage. It forms a checkpoint protein complex with RAD1 and HUS1. This complex is recruited by checkpoint protein RAD17 to the sites of DNA damage, which is thought to be important for triggering the checkpoint-signaling cascade. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
- Molecular Weight
- 42.4 kDa
- NCBI Accession
- NP_004575
- Pathways
- Positive Regulation of Response to DNA Damage Stimulus
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