RASSF8 Protein (Myc-DYKDDDDK Tag)

Catalog No. ABIN2730575

Product Details

Target: RASSF8 (Ras Association (RalGDS/AF-6) Domain Family (N-terminal) Member 8 (RASSF8))

Protein Type: Recombinant

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This RASSF8 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human RASSF8 protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: RASSF8 (Ras Association (RalGDS/AF-6) Domain Family (N-terminal) Member 8 (RASSF8))

Alternative Name: Rassf8 (RASSF8 Products)

Synonyms: c12orf2 Protein, rassf8 Protein, wu:fb96e06 Protein, zgc:64017 Protein, C12orf2 Protein, HOJ1 Protein, 5133400D11Rik Protein, AA815821 Protein, AW123240 Protein, Hoj1 Protein, mHoj-1 Protein, RGD1308820 Protein, Ras association domain family member 8 Protein, Ras association (RalGDS/AF-6) domain family (N-terminal) member 8b Protein, Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 Protein, RASSF8 Protein, rassf8b Protein, Rassf8 Protein

Background: This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(1222)(p11.2q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 45.3 kDa

NCBI Accession: NP_009142

Pathways: Chromatin Binding