Retinoblastoma Binding Protein 4 Protein (RBBP4) (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2730578

Product Details

Target: Retinoblastoma Binding Protein 4 (RBBP4)

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 1

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This Retinoblastoma Binding Protein 4 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human RBBP4 / RBAP48 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: Retinoblastoma Binding Protein 4 (RBBP4)

Alternative Name: Rbbp4,rbap48 (RBBP4 Products)

Synonyms: NURF55 Protein, RBAP48 Protein, 154659_at Protein, 55 Protein, CAF-1 Protein, CAF1 Protein, CAF1-55 Protein, CAF1p55 Protein, CG4236 Protein, Caf-1 Protein, Caf1/p55 Protein, Caf1p55 Protein, Dmel\\CG4236 Protein, MSI1/RbAp48/CAC3/LIN-53 Protein, NURF Protein, NURF-55 Protein, Nurf Protein, Nurf 55 Protein, Nurf-55 Protein, Nurf55 Protein, P55 Protein, RbAp48 Protein, S(ls)3 Protein, caf-1 Protein, caf1 Protein, caf1 p55 Protein, d-CAF1 Protein, dCAF-1 Protein, dCAF-1 p55 Protein, dNURF Protein, p55 Protein, p55 CAF1 Protein, p55/NURF-55 Protein, p55CAF1 Protein, nurf55 Protein, rbap48 Protein, xrbbp4 Protein, mRbAp48 Protein, RBBP4 Protein, rbb4-2 Protein, zgc:55349 Protein, zgc:77854 Protein, wu:fb33a09 Protein, wu:fb40e10 Protein, RBBP-4 Protein, rbbp4 Protein, M4E13.110 Protein, M4E13_110 Protein, MULTICOPY SUPPRESSOR OF IRA1 3 Protein, NFC3 Protein, NUCLEOSOME/CHROMATIN ASSEMBLY FACTOR GROUP C 3 Protein, RB binding protein 4, chromatin remodeling factor Protein, Chromatin assembly factor 1, p55 subunit Protein, retinoblastoma binding protein 4 Protein, retinoblastoma binding protein 4, chromatin remodeling factor Protein, retinoblastoma binding protein 4 L homeolog Protein, Transducin family protein / WD-40 repeat family protein Protein, retinoblastoma binding protein 4 S homeolog Protein, RBBP4 Protein, Caf1-55 Protein, rbbp4 Protein, Rbbp4 Protein, rbbp4.L Protein, MSI3 Protein, rbbp4.S Protein

Background: This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. It is present in protein complexes involved in histone acetylation and chromatin assembly. It is part of the Mi-2 complex which has been implicated in chromatin remodeling and transcriptional repression associated with histone deacetylation. This encoded protein is also part of co-repressor complexes, which is an integral component of transcriptional silencing. It is found among several cellular proteins that bind directly to retinoblastoma protein to regulate cell proliferation. This protein also seems to be involved in transcriptional repression of E2F-responsive genes. Three transcript variants encoding different isoforms have been found for this gene.

Molecular Weight: 47.5 kDa

NCBI Accession: NP_005601

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases, Stem Cell Maintenance, Chromatin Binding, Protein targeting to Nucleus