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RBPJ Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

RBPJ Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2730632
  • Target See all RBPJ Proteins
    RBPJ (Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 3
    Origin
    • 5
    • 1
    • 1
    Human
    Source
    • 2
    • 2
    • 1
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This RBPJ protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human RBP-J kappa / RBPJ (transcript variant 3) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product RBPJ Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    RBPJ (Recombination Signal Binding Protein For Immunoglobulin kappa J Region (RBPJ))
    Alternative Name
    Rbp-J Kappa,rbpj (RBPJ Products)
    Synonyms
    AOS3 Protein, CBF1 Protein, IGKJRB Protein, IGKJRB1 Protein, KBF2 Protein, RBP-J Protein, RBPJK Protein, RBPSUH Protein, SUH Protein, csl Protein, AI843960 Protein, Igkjrb Protein, Igkrsbp Protein, RBP-J kappa Protein, RBPjk Protein, Rbpsuh Protein, Su(H) Protein, XSu(H) Protein, xsu(h)1 Protein, Su(H)1 Protein, Su(h)A Protein, ik:tdsubc_1e8 Protein, rbpj Protein, rbpsuh Protein, xx:tdsubc_1e8 Protein, Su(H)2 Protein, su(h)B Protein, recombination signal binding protein for immunoglobulin kappa J region Protein, recombination signal binding protein for immunoglobulin kappa J region S homeolog Protein, recombination signal binding protein for immunoglobulin kappa J region a Protein, recombination signal binding protein for immunoglobulin kappa J region b Protein, RBPJ Protein, Rbpj Protein, rbpj.S Protein, rbpja Protein, rbpjb Protein
    Background
    The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway. The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins. It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes. Several transcript variants encoding different isoforms have been found for this gene, and several pseudogenes of this gene exist on chromosome 9.
    Molecular Weight
    54 kDa
    NCBI Accession
    NP_976028
    Pathways
    Notch Signaling, Stem Cell Maintenance, Smooth Muscle Cell Migration
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