RCHY1 Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2730656

Product Details

Target: RCHY1 (Ring Finger and CHY Zinc Finger Domain Containing 1, E3 Ubiquitin Protein Ligase (RCHY1))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 1

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This RCHY1 protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human RCHY1 / PIRH2 (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: RCHY1 (Ring Finger and CHY Zinc Finger Domain Containing 1, E3 Ubiquitin Protein Ligase (RCHY1))

Alternative Name: Rchy1,pirh2 (RCHY1 Products)

Synonyms: ARNIP Protein, CHIMP Protein, PIRH2 Protein, PRO1996 Protein, RNF199 Protein, ZNF363 Protein, Pirh2 Protein, Zfp363 Protein, Znf363 Protein, wu:fb37e07 Protein, zgc:101128 Protein, RCHY1 Protein, arnip Protein, chimp Protein, pirh2 Protein, harnip Protein, rnf199 Protein, znf363 Protein, pro1996 Protein, ring finger and CHY zinc finger domain containing 1 Protein, ring finger and CHY zinc finger domain containing 1 L homeolog Protein, RCHY1 Protein, Rchy1 Protein, rchy1 Protein, rchy1.L Protein

Background: The protein encoded by this gene has ubiquitin ligase activity. It mediates E3-dependent ubiquitination and proteasomal degradation of target proteins, including tumor protein 53, histone deacetylase 1, and cyclin-dependent kinase inhibitor 1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Molecular Weight: 29.9 kDa

NCBI Accession: NP_056251