Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

RGS14 Protein (Myc-DYKDDDDK Tag)

RGS14 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2730812
  • Target See all RGS14 Proteins
    RGS14 (Regulator of G-Protein Signaling 14 (RGS14))
    Protein Type
    Recombinant
    Origin
    • 4
    • 1
    • 1
    Human
    Source
    • 2
    • 2
    • 1
    • 1
    HEK-293 Cells
    Purification tag / Conjugate
    This RGS14 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human RGS14 protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product RGS14 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    RGS14 (Regulator of G-Protein Signaling 14 (RGS14))
    Alternative Name
    Rgs14 (RGS14 Products)
    Synonyms
    RPIP1 Protein, MGC80558 Protein, RGS14 Protein, rgs14 Protein, wu:fi04g12 Protein, regulator of G protein signaling 14 Protein, regulator of G-protein signaling 14 Protein, regulator of G-protein signaling 14 L homeolog Protein, regulator of G-protein signalling 14 Protein, regulator of G protein signaling 14a Protein, RGS14 Protein, Rgs14 Protein, rgs14.L Protein, rgs14 Protein, rgs14a Protein
    Background
    This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
    Molecular Weight
    61.3 kDa
    NCBI Accession
    NP_006471
    Pathways
    Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Platelet-derived growth Factor Receptor Signaling
You are here:
Support