RHOC Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)
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- Target See all RHOC Proteins
- RHOC (Ras Homolog Gene Family, Member C (RHOC))
- Protein Type
- Recombinant
- Protein Characteristics
- Transcript Variant 1
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Origin
- Human
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Source
- HEK-293 Cells
- Purification tag / Conjugate
- This RHOC protein is labelled with Myc-DYKDDDDK Tag.
- Application
- Antibody Production (AbP), Standard (STD)
- Characteristics
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- Recombinant human RhoC (transcript variant 1) protein expressed in HEK293 cells.
- Produced with end-sequenced ORF clone
- Purity
- > 80 % as determined by SDS-PAGE and Coomassie blue staining
- Top Product
- Discover our top product RHOC Protein
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- Application Notes
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Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays - Comment
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The tag is located at the C-terminal.
- Restrictions
- For Research Use only
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- Concentration
- 50 μg/mL
- Buffer
- 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
- Storage
- -80 °C
- Storage Comment
- Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
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- Target
- RHOC (Ras Homolog Gene Family, Member C (RHOC))
- Alternative Name
- Rhoc (RHOC Products)
- Synonyms
- ARHC Protein, LOC100221682 Protein, ARH9 Protein, H9 Protein, RHOH9 Protein, AI324259 Protein, Arh9 Protein, Arhc Protein, CRHOC Protein, ras homolog family member C L homeolog Protein, ras homolog family member C Protein, rhoc.L Protein, RHOC Protein, rhoc Protein, Rhoc Protein
- Background
- This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. The protein encoded by this gene is prenylated at its C-terminus, and localizes to the cytoplasm and plasma membrane. It is thought to be important in cell locomotion. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants, encoding the same protein, have been identified.
- Molecular Weight
- 21.8 kDa
- NCBI Accession
- NP_786886
- Pathways
- WNT Signaling, Cell-Cell Junction Organization
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