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RNF14 Protein (Transcript Variant 3) (Myc-DYKDDDDK Tag)

RNF14 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Catalog No. ABIN2731023
  • Target See all RNF14 Proteins
    RNF14 (Ring Finger Protein 14 (RNF14))
    Protein Type
    Recombinant
    Protein Characteristics
    Transcript Variant 3
    Origin
    • 6
    • 1
    Human
    Source
    • 3
    • 2
    • 2
    HEK-293 Cells
    Purification tag / Conjugate
    This RNF14 protein is labelled with Myc-DYKDDDDK Tag.
    Application
    Antibody Production (AbP), Standard (STD)
    Characteristics
    • Recombinant human RNF14 (transcript variant 3) protein expressed in HEK293 cells.
    • Produced with end-sequenced ORF clone
    Purity
    > 80 % as determined by SDS-PAGE and Coomassie blue staining
    Top Product
    Discover our top product RNF14 Protein
  • Application Notes
    Recombinant human proteins can be used for:
    Native antigens for optimized antibody production
    Positive controls in ELISA and other antibody assays
    Comment

    The tag is located at the C-terminal.

    Restrictions
    For Research Use only
  • Concentration
    50 μg/mL
    Buffer
    25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
    Storage
    -80 °C
    Storage Comment
    Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.
  • Target
    RNF14 (Ring Finger Protein 14 (RNF14))
    Alternative Name
    Rnf14 (RNF14 Products)
    Synonyms
    ARA54 Protein, HFB30 Protein, TRIAD2 Protein, 2310075C09Rik Protein, 2610005D23Rik Protein, AA986456 Protein, AU041447 Protein, D18Ertd188e Protein, D7Bwg0165e Protein, Triad2 Protein, ring finger protein 14 Protein, RNF14 Protein, Rnf14 Protein
    Background
    The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Six alternatively spliced transcript variants encoding two distinct isoforms have been reported.
    Molecular Weight
    53.7 kDa
    NCBI Accession
    NP_899646
    Pathways
    Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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