RORA Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Catalog No. ABIN2731073

Product Details

Target: RORA (RAR-Related Orphan Receptor A (RORA))

Protein Type: Recombinant

Protein Characteristics: Transcript Variant 1

Origin: Human

Source: HEK-293 Cells

Purification tag / Conjugate: This RORA protein is labelled with Myc-DYKDDDDK Tag.

Application: Antibody Production (AbP), Standard (STD)

Characteristics:

• Recombinant human ROR-alpha / RORA (transcript variant 1) protein expressed in HEK293 cells.
• Produced with end-sequenced ORF clone

Purity: > 80 % as determined by SDS-PAGE and Coomassie blue staining

Application Details

Application Notes: Recombinant human proteins can be used for:
Native antigens for optimized antibody production
Positive controls in ELISA and other antibody assays

Comment:

The tag is located at the C-terminal.

Restrictions: For Research Use only

Handling

Concentration: 50 μg/mL

Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.

Storage: -80 °C

Storage Comment: Store at -80°C. Thaw on ice, aliquot to individual single-use tubes, and then re-freeze immediately. Only 2-3 freeze thaw cycles are recommended.

Target Details

Target: RORA (RAR-Related Orphan Receptor A (RORA))

Alternative Name: Ror-Alpha,rora (RORA Products)

Synonyms: ror1 Protein, ror2 Protein, ror3 Protein, rzra Protein, nr1f1 Protein, MGC146531 Protein, NR1F1 Protein, ROR1 Protein, ROR2 Protein, ROR3 Protein, RZR-ALPHA Protein, RZRA Protein, RORalpha-B Protein, gb:dq017624 Protein, rora2 Protein, 9530021D13Rik Protein, Nr1f1 Protein, nmf267 Protein, sg Protein, staggerer Protein, tmgc26 Protein, RORalpha1 Protein, RAR related orphan receptor A Protein, RAR-related orphan receptor A Protein, RAR-related orphan receptor A, paralog a Protein, RAR-related orphan receptor alpha Protein, RORA Protein, rora Protein, Rora Protein, roraa Protein

Background: The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, as well as with NM23-1, the product of a tumor metastasis suppressor candidate gene. Also, it has been shown to aid in the transcriptional regulation of some genes involved in circadian rhythm. Four transcript variants encoding different isoforms have been described for this gene.

Molecular Weight: 58.8 kDa

NCBI Accession: NP_599023

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha